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三联法治疗中晚期类风湿性关节炎95例临床研究

发表时间:2018-08-01浏览次数:

  三联法治疗中晚期类风湿性关节炎95例临床研究(节录)

  (原载《中医杂志》2001年12月第42卷第12期

  摘要

  目的:

  TANTAOSANLIANLIAOFABIANZHENGZHILIAOZHONGWANQILEIFENGSHIXINGGUANJIEYAN(RA)DELIAOXIAOJIANQUANXING。

  FANGFA:

网上扎金花平台   YIFUZHENGJUANBI、HUATANQUYUWEIJIBENZHIZE,YIBIDEZHIPIANKOUFU,ZHONGYAOQILIAOYIPEIHANSHIBIYUSHUWUHUATOUPIFA,ZHENGQINGFENGTONGNINGZHENGUANJIEQIANGZHUSHE(SANLIANJIAZU)ZHILIAOYANGXUHANNING、TANYUHUJIEZHONGWANQIRA50LI;BIDEQINGYINKOUFU,ZHONGYAOQILIAOYIPEIHANREBIYUANWUHUATOUPIFA,ZHENGQINGFENGTONGNINGZHENGUANJIEQIANGZHUSHE(SANLIANYIZU)ZHILIAOYINXUREYU、TANYUHUJIEZHONGWANQIRA45LI;BINGYIXIAOYANTONGNEIFUJIAJIZHUJIAANDIELING(MTX)ZHILIAOZHONGWANQIRA43LIZUODUIZHAOYANJIU。

  JIEGUO:

  SANLIANJIAZUDUIZHONGWANQIRAZHONGYIZHUZHENGKONGXIANLV、YOUXIAOLVFENBIEWEI74%、26%HE86%、14%;SANLIANYIZUDUIZHONGWANQIRA、ZHONGYIZHUZHENGKONGXIANLV、YOUXIAOLVFENBIEWEI:73.34%、26.66%HE86.67%、13.33%;DUIZHAOZUDUIZHONGWANQIRA、ZHONGYIZHUZHENGKONGXIANLV、YOUXIAOLVFENBIEWEI:27.91%、46.51%HE23.26%、37.21%。SANLIANJIA、YIZUFENBIEYUDUIZHAOZUBIJIAO,ANRiditJIANYAN,YOUFEICHANGXIANZHUXINGCHAYI(P<0.01);QIESANLIANJIAZU、YIZULINCHUANGZHENGZHUANG、TIZHENG、YANZHENGZHISHU、XUECHEN(ESR)、CFANYINGDANBAI(CRP)、LEIFENGSHIYINZI(RF)DIDU、MIANYIQIUDANBAIG(IgG)、MIANYIQIUDANBAIM(IgM)、XUEQINGBUTIC3(C3)、XUEHONGDANBAI(Hb)ZHILIAOQIANHOUFENBIEBIJIAO,CHAYIYOUFEICHANGXIANZHUXING(P<0.01),YUDUIZHAOZUBIJIAOCHAYIYOUXIANZHUXING(P<0.05HUOP<0.01)。

  JIELUN:

SANLIANLIAOFADUIRAZHONGQIBINGQINGKONGZHIYOUWEITUCHU,DUIWANQIRAHUANZHETIGAOSHENGHUOZHILIANGJIAOWEIMINGXIAN,QIEJIAOANQUAN。

  讨论:

网上扎金花平台   ZHONGWANQIRASHUYUZHONGYIXUE“WANGBI”、“LIJIEBING”DENGFANCHOU。BINGYINBINGJIJIAOFUZA,BINGQINGSHENZHONG,LINCHUANGYIJIANGYING、ZHONGTONG,GUANJIEBIANXING,JINSUOROUJUAN,BUNENGQUSHEN,GUZHISHOUSUN,CHANMIANNANYU。GAIKUOBINGYINBINGJIZHUYAOYOUXIE、YU、XUSANDAFANGMIAN。QIZHUYAOBINGJIWEIGAN、PI、SHENQIXUEKUIXU,HANSHISHENQINRUSHEN,HANSHIHUJIE,NINGZUMAILUO,JINGLUOXURE,HANRECUOZA,HANSHI、TANZHUO、YUXUEDENGHUWEIJIAOJIE,FENGSHIBIZU,ZANGFUZHIXUZHUYAOZAISHEN、PI,BINGLIXINGZHIBENXUBIAOSHI、XUSHIJIAZA,QIEYOUHANRE、YIN、YANGZHIBIE,LINCHUANGDUOJIANYANGXUHANNING、TANYUHUJIEHEYINXUREYU、TANYUHUJIELIANGDAZHENGHOU,JIANJIAQIXUE、PIWEIKUIXU。GUNIFUZHENGJUANBI、HUATANXIAOYUWEIYUANZE,BINGZHENDUIBUTONGDELINCHUANGZHENGHOUFENBIEZHIDINGLIAOFA。WOZEJIANQING,CHANGFANFUFAZUO。SHEDAN,MAICHENXISHU。

网上扎金花平台   YANGXUHANNING、TANYUHUJIEZHENGZHIRA,YINGYIWENJINGSANHAN,CHUSHITONGLUO,HUATANXIAOYU,YIQIBUXU,KANGYANXIAOZHONGZHITONGDENGGONGXIAODEBIDEZHIPIANZHILIAO。GAIYAOSHIYANYANJIUZHENGMINGDUIDUOZHONGZHIYANJISUOYINQIDESHIYANXINGZHONGZHANGHEMAOXIXUEGUANTONGTOUXINGZENGGAOJUNYOUXIANZHUDEYIZHIZUOYONG,NENGXIANZHUYIZHIROUYAZHONGXINGCHENGHEMINGJIAOYINQIDEXIAOBAISHUFUQIANGYEZHONGBAIXIBAOSHENGGAO,BIAOMINGBIDEZHIPIANWULUNDUIYANZHENGZAOQIHUODISANQIZUZHIZENGSHENGHEROUYAZHONGXINGCHENGJUNYOUXIANZHUDEYIZHIZUOYONG;KEXIANZHUYIZHIDABAISHUZUOJIXINGGUANJIEYANZHIZAOQISHENCHUXINGYANZHENGHEHOUQIJIFAXINGSUNHAI,ZHENGMINGTAYOUMIANYIYIZHIHEDIAOJIEZUOYONG;QIEYOUFEICHANGXIANZHUDEZHENTONGZUOYONG。

网上扎金花平台   XUREYU、TANYUHUJIEZHENGZHIRA,NIZISHENQINGRE、HUATANQUYUDENGZUOYONGDEBIDEQINGYINZHILIAO,GAIYAOSHIYANYANJIUZHENGMING,YOUFEICHANGXIANZHUDEKANGYANXIAOZHONGZHITONG,MIANYIYIZHIHESHUANGXIANGDIAOJIEDENGGONGXIAO。PEIZHENGQINGFENGTONGNINGGUANJIEQIANGZHUSHE,YIZENGQIANGBIDEZHIPIAN、BIDEQINGYINQUXIETONGLUODENGGONGXIAO,SHIYANYANJIUZHENGSHIJUYOUFEICHANGXIANZHUDEKANGYANXIAOZHONGZHENTONG,MIANYIYIZHIZUOYONG。GAIYAOZHUSHEZHIBINGXIELIULIANZHICHU,ZHIJIEFAHUIZUOYONG,YIZHIHUOKONGZHIGUANJIEBINGBIANZUZHIDEBINGLIZHUANGTAI,SHIBINGBIANBUWEIDEQIXUETONGCHANG,SHISHIHENGDEGUANJIEZHANGAIGONGNENGHUODONGHUIFUHUOXIANZHUGAISHAN。ZUOZHONGYAOQILIAOYIANZHENGXINGXUANPEIYAOWU,CHANSHENGDEHANYAOQITIWUHUAQUANSHENJIFU、KONGQIAO、JINGXUEDENG,SHENTOU、XISHOU、KUOSAN、FUSHEDENGTUJINGSHENRUCOULI、ZANGFU,KEZHIJIEFAHUIWENJINGSANHAN、QUFENGCHUSHI,QINGRETONGLUO,HUATANQUYU、FUZHENGGUBENDENGGONGXIAOHEJIANJIEDEWULIWENREZUOYONG,CUSHICOULIFAXIE,XUEGUANKUOZHANG,SHITINEIWAIGOUTONG,JIASUQIXUEYUNXINGTONGCHANG,JITIDAIXIEZENGQIANG,CUJINZUZHIZAISHENGNENGLI,DIAOZHENGJITIMIANYIPINGHENG,YIJIZHILIAOHOUGENGYOULIYUHUANZHEJIAQIANGGONGNENGDUANLIANHEJIZAOHUIFUJINENGZHANGAIDEYOULICUOSHI。NEIWAILIANHEBIANZHENGYINGYONGSANLIANLIAOFA,QIEZHONGRABINGYINBINGJI,FAHUINEILIANWAILUODEZHENGTIYUJUBUDIAOJIEHEYIDEYOUSHI,TIGAOYIZHILEYANZHENGJIEZHIPG2DEHANLIANG,DADAOJIAOKUAIDEKANGYANZHENTONGZUOYONG;JIAOQIANGDEYIZHITIYEMIANYIHEDIAOJIEXIBAOMIANYIDESHUANGZHONGZUOYONG;CONGERHUIFUJITIZHENGCHANGDEMIANYIGONGNENG;YIZHIIL-lYICHANGCHANSHENGDEZUOYONG,ZUZHIGUZHIPOHUAIDEFASHENGHEFAZHAN,GAIBIANBINGQINGDEZHILIAOXIAOGUO;TIGAONEIYUANXINGKANGYANGHUAMEISODDEHUOXING,ZENGQIANGJITIKANGYANGHUAXITONGDENENGLI,YIQINGCHUGUODUODEZHIZHIGUOYANGHUAWU(LP0);JIANQINGZIYOUJIDUIGUANJIEDEBINGLISUNSHANG;JIANGDIXUEJIANGXUESHUANSUA2(TXA2)DEDAIXIECHANWU——XUESHUANWANB2(TXB2)HANLIANG,XIANLESHIYUZU、GUANJIEJIANGYING、GONGNENGZHANGAICHENGDUDENGZHILIAOHOUDEDAOXIANZHUDEJIANQING,CHONGFENTISANLIANLIAOFAXIANGHUQUZHANGBUDUAN,QIEZHONGRADEBINGLIGUOCHENGDENGTEDIAN,FEICHANGXIANZHUTIGAOLELINCHUANGXIAOGUO,JIANXIAOKUAI,QIXIAOZUIDUAN4TIAN,ZUIZHANG7TIAN,FUZUOYONGSHAO。QIESHIZHONGWANQIRADEBINGQINGDEDAOYOUXIAODEKONGZHIHEZHIYU。GUANYUDUISHANGSHULIANGZHENGZHONGQITAJIANZHENGLIAOXIAODEYINGXIANG:ZAILINZHENGZHONGGUANCHADAOERZHENGZHONGJIANZHENGJUYOUYIDINGDEBILI,CONGSHEJISANLIANLIAOFAZHONGJIBENKAOLVDAOJIANZHENGDEZHILIAOHECHULI,DUIQIXUEKUIXUJIAOZHONGDEHUANZHEXUANYONGYIQIBUXUE,JIANPIHUWEI,RUNYANGFEIXUZHIAJIAO、YANGTIGEN、XIYANGCAN、FULING、LVMEIHUA、MAIDONG、BAIBU、XINGRENDENG,ZHONGYAOQILIAOYIZHILIAODEWENDUKONGZHIZAI40℃ZUOYOU,ZHILIAOSHEJISHIJIANMEICI15FENZHONG,DAIBINGQINGHAOZHUANHOUZHUBUZENGJIADAO20~30FENZHONG。ZHUYISHIXIANG:(1)DUIBAIXIBAOJIANSHAOZHENG、GUOMINTIZHI、XIAOCHUANBINGHUANZHEYINGSHENYONGZHENGQINGFENGTONGNING。(2)LINCHUANGYINGYONGZHONGYAOQILIAOYISHIBIXUYAOYANGEZHANGWOSHIYINGZHENG、JINJIZHENGHEZHUYISHIXIANG。

  江苏省中西医结合风湿病研究中心 张安林 顾宝新

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